If you pick "It's already happened! Mass Effect Wiki Guide. Last Edited: 21 Sep am. Virmire is unlocked by completing two of the three initial Missions Worlds: Feros , Noveria and Therum. As well, there's no punishment for saving Virmire for last and doing the other Mission World instead. These are spoilers for Virmire.
Do not keep scrolling if you're only looking for a walkthrough. Instead, use the links above to get to the part of the walkthrough you're looking for. Unfortunately, the political instability of the nearby Terminus Systems has impeded colonization efforts - the high risk of raids by pirates and slavers makes it an unappealing homestead.
Virmire is a lush world located on the frontier of the Attican Traverse. Only the political instability of the region has impeded efforts at colonization. Many times, the Citadel has opened negotiations to settle Virmire with the various criminal gangs and petty dictatorships in the nearby Terminus Systems. All fell apart due to internal power shifts within the opposing parties. Be warned: This scenario here can end in one of two ways - with Wrex alive, and understanding, or with Wrex dead, executed for being a liability.
If alive, Wrex will appear in both the second and third Mass Effect games - and in Mass Effect 3 in particular, a Paragon Shepard will have an easier time achieving the best outcome in a major storyline if he is alive - while Renegade Shepard arguably benefits more if he is dead. Ashley and Kaidan both volunteer themselves to go with the Salarians. You have to choose between the two of them. You can then take the other Alliance soldier with you on your assault.
Keep in mind that Ashley has the skill set of the Soldier Class , while Kaidan more closely resembles the Sentinel class. Send the other with Kirrahe. You'll come to a junction; while both lead the same way, the enemies on each path differ. Next, you'll come to an uplink tower. Keep heading forward until a member of the other team mentions Geth Flyers or airborne enemies. Destroy the drones and tank here before making your way back or west to the base entrance.
Clear the entrance and enter through the door on the right of the bridge or decrypt the entrance to the left down a ramp, which bypasses some enemies and takes you to the Maintenance Bay. If you went left, you might choose to head up to the Base Entry area anyway to bypass an alarm, rerouting enemy forces to Kirrahe's team. You can get there by heading to the upper level and past the Security Office to the Warehouse. This option is on the way through the other entrance.
You can head to the labs or cell blocks, but we recommend going through Cell Block A, then B to encounter some extra characters. Go to the right of the elevator to reach Cell Block A and defeat the enemies there, including the indoctrinated salarian scientists.
Shepard will encounter a member of the captured salarian team with some interesting information about other research being done here. Talking to him gives Shepard access to the other holding cells where his broken team members are held. After the encounter, head back the way you came and over to Cell Block B to the left of the elevator.
Here you'll encounter another, less fortunate salarian team member. Afterward, you can head to the other end of the room and down to the Storage Room and Maintenance Bay if you didn't explore that area earlier. Head back up to the Base Entry and take the elevator down to the Genophage Labs.
Enemies won't notice you right away, giving you a chance to get in position. The Husks in containment will release during combat; otherwise, the krogan doctor is the main threat. Defeat the enemies and search the room for items before heading through the exit near the center of the lab. If the bridge is up, head back into the labs and access the Geth console to the left. Cross the bridge and head into the Security Office on the left, where you'll find an asari scientist.
She can give Shepard more information about indoctrination and the facility, including access to Saren's Communication Tower. Search the office before taking the elevator down to the Communication Tower.
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